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Geburtshilfe Frauenheilkd 2008; 68(2): 178-180
DOI: 10.1055/s-2007-965225
Fallbericht

© Georg Thieme Verlag KG Stuttgart · New York

Rosai-Dorfman Disease with Breast Involvement

Rosai-Dorfman-Erkrankung mit Befall der BrustD. Opric1 , D. Gugic2 , J. Fajdić3 , Z. Hrgovic4 , M. Granic5 , S. Opric5
  • 1Institut of Pathology, Medical Faculty, Belgrade, Serbia
  • 2Institute of Oncology, J.-J.-Strossmeyer University, Osijek, Croatia
  • 3General Hospital, Pozega, Croatia
  • 4Department of Obstetrics and Gynecology, J.-J.-Strossmeyer University, Clinic Hospital Osijek, Croatia
  • 5Clinical Center “Bežanijska kosa”, Belgrade, Serbia
Further Information

Publication History

received 7.10.2005 revised 27.10.2005

accepted 10.7.2007

Publication Date:
26 February 2008 (online)

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Abstract

The authors present a case of Rosai-Dorfman disease with breast involvement. The initial diagnosis was breast malignancy with metastatic deposits in the axillary lymph nodes. The correct diagnosis was only made after a second histological investigation was carried out with immunohistochemical determination of S-100 protein and CD68. Rosai-Dorfman disease is a rare, benign histiocytic proliferation disorder.

Zusammenfassung

Es wird ein Fall von Rosai-Dorfman-Erkrankung vorgestellt mit Befall der Brust. Zunächst lautet die Diagnose auf eine maligne Erkrankung der Brust mit Metastasen in den Achsellymphknoten. Die richtige Diagnose wurde erst gestellt nach einer zweiten histologischen Untersuchung mit immunhistochemischer Bestimmung von S-100-Protein und CD68. Die Rosai-Dorfman-Erkrankung ist eine seltene, in der Regel gutartig verlaufende Sinushistiozytose.

Key words

histiocytic proliferation - Rosai‐Dorfman - S‐100 protein - CD68

Schlüsselwörter

histiozytäre Proliferation - Rosai‐Dorfman - S‐100‐Protein - CD68

References

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Prof. Dr. med. Zlatko Hrgovic

Kaiserstraße 15

60311 Frankfurt/Main

Germany

Email: info@hrgovic.de

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